Photoisomerization Control Mechanisms in Protonated Schiff Bases
نویسندگان
چکیده
منابع مشابه
Photoisomerization Control Mechanisms in Protonated Schiff Bases
880-Pos Board B649 Dynamics of Amyloid Beta-Peptide (21-30) and its Iowa Mutation under Confinement and Crowding: A Molecular Dynamics Study Srinivasa Rao Jampani, Luis Cruz. Drexel University, Philadelphia, PA, USA. We present long time all-atommolecular dynamics simulations of the wild type (WT) and Iowa mutation of the amyloid b-protein (Ab) fragment (21-30) under confinement and crowding. T...
متن کاملControl Mechanisms of Photoisomerization in Protonated Schiff Bases.
We performed ab initio excited-state molecular dynamics simulations of a gas-phase photoexcited protonated Schiff base (C1-N2═C3-C4═C5-C6) to search for control mechanisms of its photoisomerization. The excited molecule twists by ∼90° around either the N2C3 bond or the C4C5 bond and relaxes to the ground electronic state through a conical intersection with either a trans or cis outcome. We show...
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Retinal is one of Nature's most important and widespread chromophores, exhibiting remarkable versatility in its function and spectral response, depending on its protein environment. Reliable spectroscopic and photochemical data for the isolated retinal molecule are essential for calibrating theoretical approaches that seek to model retinal's behaviour in complex protein environments. However, d...
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A visual pigment is composed of retinal bound to its apoprotein by a protonated Schiff base linkage. Light isomerizes the chromophore and eventually causes the deprotonation of this Schiff base linkage at the meta II stage of the bleaching cycle. The meta II intermediate of the visual pigment is the active form of the pigment that binds to and activates the G protein transducin, starting the vi...
متن کاملRetinal shows its true colours: photoisomerization action spectra of mobility-selected isomers of retinal protonated Schiff base†
Retinal is one of Nature’s most important and widespread chromophores, exhibiting remarkable versatility in its function and spectral response, depending on its protein environment. Reliable spectroscopic and photochemical data for the isolated retinal molecule are essential for calibrating theoretical approaches that seek to model retinal’s behaviour in complex protein environments. However, d...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.11.969